PeproTech is proud to be able to continue to support you in the midst of unprecedented challenges pertaining to the COVID-19 virus. For more information, click here.

Research Areas

Cancer

Cellular proliferation represents an important element within a broad spectrum of physiological processes responsible for the assurance of normal development and maintenance, including fertilization and early development, population growth, and normal tissue maintenance and repair.  Therefore, a vast number of mechanisms have evolved to ensure the regulation and proper progression of the proliferation process.  Although corruption of normal cellular proliferation is minimized with the existence of these checkpoints and safeguards functioning to ensure the prevention, identification, and rectification of abnormal progression through the phases of cellular division, unmitigated proliferation can be provoked by instances of spontaneous genomic mutations, or those mutations resulting from a physical or chemical mutagen.  Unrestrained cell proliferation that defies the normal constraints of cellular division is the defining feature of cancer, which results from a culmination of mutations causing, among other attributes, decreased density-dependent growth inhibition, anchorage-independence, telomerase production, decreased dependence on external growth factors, inhibition of cell cycle control mechanisms, the inhibition of controlled apoptosis of damaged cells, and an excessive accumulation chromosomal abnormalities.  Although unrestricted proliferation is a defining feature of cancerous cells, it is not this defiance of normal cell cycle regulation, but rather the ability to evade immune responses and the possibility for those cells to spread invasively, that introduce the potential for malignancy.  Modern cancer research focuses on the comprehension of those pathways responsible for both normal and abnormal cellular proliferation, the significance of cell cycle regulators within these pathways, those mutations contributing to the evasion these constraints, those genomic errors and mutagens responsible for such mutations, and the pathways for the development and metastasis of cancerous cells, among numerous other aspects, for advancements in developing innovative methods of prevention and treatment.

Explore relevant products below.

友情链接:摆脱游戏平台  电子游艺娱乐平台_Welcome  电竞赛事竞猜_王者荣耀赛事_中国电竞竞猜网  葡京平台|葡京赌城官网  电竞下注平台|app下载  糖果派对游戏官网  糖果派对游戏官网  葡京app_葡京官网  电竞下注平台|在线网址  银河开户_银河集团_银河注册官网